Children's Hospital of Philadelphia Study May Help Explain Why Some Children with Sepsis or Organ Failure Face a Harder Recovery

A Children's Hospital of Philadelphia (CHOP) research team, working with collaborators across Penn and several national institutions, reported that many critically ill children who develop multiple ...
Science Daily

Cell aging in one organ can snowball into multi-organ failure

The aging and failure of cells that occurs when one part of the body is damaged can spread to other organs, a study suggests. The ageing and failure of cells that occurs when one part of the body is ...
Nature

Organ Dysfunction Assessment in Critical Care

Assessment of organ dysfunction lies at the heart of contemporary critical care, offering an objective framework to quantify the severity and progression of multi-organ impairment in the intensive ...
EurekAlert!

The international system for assessing organ dysfunction in critically ill patients is updated after thirty years

The Journal of the American Medical Association (JAMA) has recently published the updated version of the Sequential Organ Failure Assessment (SOFA), the global reference system in intensive care ...
Frontiers

Endothelial Dysfunction, Vascular-Organ Crosstalk, and Therapeutic Targets in Cardiovascular Disease

Cardiovascular disease (CVD) remains a leading cause of morbidity and mortality worldwide. A growing body of evidence identifies endothelial dysfunction as ...